In hematology, essential thrombocythemia (ET) is a rare chronic blood cancer (myeloproliferative neoplasm) characterised by the overproduction of platelets (thrombocytes) by megakaryocytes in the bone marrow. It may, albeit rarely, develop into acute myeloid leukemia or myelofibrosis. It is one of the blood cancers wherein the bone marrow produces too many white or red blood cells,。
Overview: Essential thrombocythemia is a Janus kinase 2 (JAK2) mutation-prevalent myeloproliferative neoplasm characterized by clonal thrombocytosis; clinical course is often。
Pacientii cu trombocitemie esentiala au o supravituire la 10 ani de 64%-80% care nu este diferita de cea a populatiei generale. Decesul apare prin complicatii trombotice. Transformarea in leucemie acuta mieloblastica apare la 0,6%-5% trombocitemie esentialadin pacienti si acest。
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